- Original Article
- Possible Neuroprotective Role of Exogenous Growth Hormone on Hypoxic-Ischemic Brain Injury in Neonatal Rats
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Young Pyo Chang, Mi Kyung Jung, Youn Hee Jee, Jae Ju Cho, Soon Bum Lee, Woo Sung Park, Jong-Wan Kim, Dong Hoon Shin
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Clin Exp Pediatr. 2004;47(11):1210-1215. Published online November 15, 2004
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Purpose : This study was performed to evaluate the possible neuroprotective effect of exogenous growth hormone on hypoxic-ischemic brain injury in neonatal rats.
Methods : After ligation of the right common carotid artery, seven-day old Sprague-Dawley rats(n= 75) were exposed to 8% oxygen for two hours. In a growth hormone(GH)-treated group(n=25), each animal was subcutanously injected by GH(50 mg/kg, Grotrpin ,... |
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